CAS No.: 1642303-38-5
(6AR,9aS)-2-(4-(6-fluoropyridin-2-yl)benzyl)-5-methyl-3-(phenylamino)-5,6a,7,8,9,9a-hexahydrocyclopenta[4,5]imidazo[1,2-a]pyrazolo[4,3-e]pyrimidin-4(2H)-one phosphate Catalog No. CSN17982
Synonyms: ITI214 Phosphate
ITI-214 is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = 58 pM).
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT03257046 Parkinson Disease Phase 1 Phase 2 Recruiting August 2018 United States, Georgia ... more >> Atlanta Center for Medical Research Recruiting Atlanta, Georgia, United States, 30331 United States, North Carolina Duke Early Phase Research Unit Recruiting Durham, North Carolina, United States, 27708 Collapse << NCT03387215 Heart Failure, Systolic Phase 1 Phase 2 Recruiting December 2019 United States, Maryland ... more >> Johns Hopkins University Recruiting Baltimore, Maryland, United States, 21287 Principal Investigator: Nisha Gilotra, MD United States, North Carolina Duke Clinical Research Institute Recruiting Durham, North Carolina, United States, 27710 Collapse << NCT03489772 Healthy Volunteers Phase 1 Recruiting June 2019 United States, Oklahoma ... more >> Laureate Institute for Brain Research, Inc. Recruiting Tulsa, Oklahoma, United States, 74136 Principal Investigator: Sahib S Khalsa, MD, PhD Collapse << - 更多
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1642303-38-5 | 储存条件 |
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| 分子式 | C29H29FN7O5P | 运输 | 蓝冰 | |||
| 分子量 | 605.56 | 别名 | ITI214 Phosphate | |||
| 溶解度 |
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动物实验配方 |
